The results showed that DcR3 siRNA alone did not slow tumor growth (Fig 6A) or reduce tumor weight (Fig 6B); however, DcR3 siRNA enhanced the inhibitory effect of gemcitabine, which is related with the enhanced downregulation of DcR3 in the tumor tissue as measured by an ELISA (Fig 6C). The gene discussed is TNFRSF6B; the disease is neoplasm.