Compared with SW480, a human colon adenocarcinoma cell line that is known to express high levels of DcR3, as compared to other 13 cell lines [22], the AsPC-1 and MiaPaCa-2 cells had an even higher level of DcR3 (Fig 2 A), which is consistent with other reports [23], [24]. This evidence concerns the gene TNFRSF6B and colon adenocarcinoma.