In particular, Nilius and co-workers suggest that menthol (TRPM8 agonist) accelerates cell migration of glioblastoma cells (Wondergem et al., 2008); on the other hand, pharmacological agents inhibiting TRPM8 reduce cell speed of prostate cancer cells (Valero et al., 2012). This evidence concerns the gene TRPM8 and Familial prostate cancer.