We identified proteins involved in host immunity to bacterial infection, such as Ndp52 [35], [36], Tax1pb1 [37], and STAT3 [38], however, human targets of the Mtb proteins were not significantly enriched for annotated pathways in the Kyoto Encyclopedia of Genes and Genomes (KEGG) when corrected for multiple testing, which may reflect the limited number of human targets found. This evidence concerns the gene STAT3 and bacterial infectious disease.