IL4R and leishmaniasis: In order to investigate the role of IL-4Rα signaling on DCs during cutaneous Leishmaniasis, CD11ccreIL-4Rα-/lox mice were infected subcutaneously with 2×106 stationary phase metacyclic promastigotes of L. major LV39 (MRHO/SV/59/P; Figure 2A, 2B and 2C) or with a more virulent GFP-expressing L. major IL81 (MHOM/IL/81/FEBNI; Figure 2D, 2E and 2F) strains into the hind footpad.