PPARD and skin carcinoma: Our previous gene expression analyses indicated a higher expression of the tyrosine kinase Src, a well-characterized proto-oncogene and enhancer of skin carcinoma (Guasch et al, 2007; Joseloff et al, 2002; Matsumoto et al, 2003; Matsumoto et al, 2004; Serrels et al, 2009; Yagi et al, 2007), in wild-type versus Pparβ/δ−/− primary keratinocytes (supplementary Fig S3A) (Montagner et al, 2011).