A truncated form of this toxin conjugated to mutated interleukin IL-13 (mhIL-13-PE, marketed under the name Cintredekin Besudotox) specifically binds and kills glioma cells while sparing normal neural cells that lack the glioma-specific receptor for the interleukin (IL13Rα2) [55]. The gene discussed is IL13RA2; the disease is central nervous system cancer.