MYCN (or N-Myc) is a proto-oncogene that normally encodes a transcription factor involved in regulating cell cycle progression, apoptosis, cell proliferation and neurogenesis [106,107] and it is overexpressed in neuroblastoma, medulloblastoma, and Wilm’s tumor [108,109,110,111,112]. The gene discussed is MYCN; the disease is Nephroblastoma.