PARP1 and neoplasm: Many PARP1 inhibitors (e.g., Veliparib, CEP-9722, Rucaparib, E7016, BMN-673, etc.) are now being evaluated both as single agents and in combinatorial approaches in a number of tumor types (see [67]), and Olaparib (KuDOS Pharmaceuticals; KU-0059436 or AstraZeneca; AZD-2281) is perhaps the best-known PARP1 inhibitor in clinical trials (see [68] for current clinical trial updates).