In the human lung cancer synergistic regulatory network, we identified a total of eight types of synergistic motifs consisting of a miRNA, a TF, and their synergistically regulated target genes, including full regulation, miRNA- or TF-leading synergistic regulation, miRNA- or TF-mediated FFL regulation, co-regulation, and miRNA- or TF-mediated cascade regulation. This evidence concerns the gene TF and lung carcinoma.