Curcumin inhibits STAT3 activation in various cell lines including multiple myeloma [89], pancreatic cancer cell lines [90], Hodgkin's lymphoma [91], head and neck squamous cell carcinoma [92], primary effusion lymphoma [93], human chronic myelogenous leukaemia [94] and ovarian cancer [95]. The gene discussed is STAT3; the disease is head and neck squamous cell carcinoma.