These results were also in agreement to the findings of Noack B., et al [3] who stated that the level of raise in CRP levels in periodontitis patients relies on the severity of the disease after adjusting for age, BMI, smoking and it was also stated that raise in CRP levels were seen coupled with infections of subgingival organisms and is frequently connected with periodontal disease [3].In studies of patients following an MI, those who have high TNF-α levels have the highest rate of recurrent cardiovascular events [12]. This evidence concerns the gene CRP and periodontal disorder.