CYCS and cancer: Magainin are shown to access the cytosolic compartment of cancer cells and cause the mitochondrial pathway of apoptosis via a mechanism that involves cytochrome c release into cytoplasm and an amplified proteasome activity, confirming its apoptotic effect (all these mechanisms are shown in Figure 1) (Westerhoff et al., 1989; Cruz-Chamorro et al., 2006).