NFKB1 and hepatocellular carcinoma: As shown in Figure 7A, the RT-qPCR analyses showed that the mRNA expression of TLR3, NF-κB, caspase-8 and IFN-γ in liver tumors of the HCC rats was all significantly up-regulated by BM-06, poly I:C or BM-06 plus sorafenib.