EGLN3 and colorectal carcinoma: We also evaluated the effect of 5-Aza-2’-deoxycytidine (5-dAzaC), an inhibitor of DNA methyltransferases (DNMTs), on the DNA methylation level of the PHD3 gene and its effect on PHD3 transcript and protein levels in HCT116 and DLD-1 CRC cells under hypoxic and normoxic conditions.