IL1B and colorectal carcinoma: Thus, carriers of the variant allele of IL1B G-1464C and T-31C were at 1.40 (95%CI: 1.05-1.86) and 1.47 (95%CI: 1.11-1.95) fold increased risk of CRC, respectively, whereas carriers of the variant allele of C-3737T were at reduced risk of CRC (IRR=0.66, 95% CI: 0.49-0.89).