The landscapes of candidate drivers differed greatly between the intrinsic subgroups of FBC, and only ARHGAP30 (Basal-like and HER2), TAF4 (Basal-like), SPAG5 (HER2 and Luminal A) and COG3 (Luminal A) were shared with MBC. The gene discussed is SPAG5; the disease is complete blood cell count.