Kota et al. reported that miR-26a can inhibit cancer cell proliferation in an HCC mouse model [28], and later studies reported that miR-26 inhibited the G1/S transition by activating the pRb protein [29] and miR-26a suppressed tumor growth by the IL-6-stat3 signaling pathway [31]. This evidence concerns the gene IL6 and hepatocellular carcinoma.