As shown in Figure 4A, macrophages isolated from HCC tumor tissue expressed significantly higher levels of VEGFA and PDGFB mRNA compared to those detected in non-tumor-infiltrating macrophages (approximate 2.07-fold upregulated, P = 0.015 and approximate 2.33-fold upregulated, P = 0.011, respectively, n = 7). The gene discussed is VEGFA; the disease is neoplasm.