TERT and lung cancer: The rs402710 is located in intron 4 of the CLPTM1L gene on chromosome 5p15.33, which contains two biologically relevant genes for lung cancer, TERT (telomerase reverse transcriptase) and CLPTM1L. The copy number gain of this region of chromosome 5p is the most frequent cytogenetic event in the early stages of NSCLC [41].