TLR4 and invasive breast carcinoma: Similarly, presence of the minor variant of the non-synonymous TLR4 rs4986790 A/G SNP, in which aspartic acid 299 is replaced by glycine, was associated with a modest increase in BrCa risk (OR = 1.81; 95% CI = 1.23, 2.66) in a Greek cohort (18).