CRH and Anorexia: In keeping with this tenant, the reversal of 5-HT-induced anorexia by α-helical CRF(9–41) in rainbow trout, as previously observed in goldfish (De Pedro et al., 1997) and mammals (Grignaschi et al., 1996), suggests that the anorexic actions of 5-HT are at least partially mediated by CRF-secreting neurons.