We sought to identify endogenous capabilities and behaviors of NSCs isolated from CaMK2α-hKO mice, a member of a family of mutants possessing dentate gyrus immaturity (including increased neurogenesis) as well as phenotypic alterations (altered GABAergic and inflammation status) and conserved behavioral correlates (social interaction deficits and cognitive impairment) of schizophrenia/bipolar disorder. The gene discussed is CAMK2A; the disease is schizophrenia.