CAMK2A and bipolar disorder: CaMK2α-hKO mice possess constitutively higher levels of neurogenesis and display elevated levels of calretinin, PSA-NCAM and doublecortin and reduced levels of mature neuronal markers, most notably calbindin.7 Many iDG models also display hypoGABAergic function and altered numbers of interneurons, key features in schizophrenia/bipolar disorder.