NSDHL and CK syndrome: Moreover, a recent study reported that mutations in nsdhl are linked to the CK syndrome, an X-linked recessive intellectual disability syndrome (McLarren et al. 2010), as well as the CHILD (congenital hemidysplasia with ichthyosiform nevus and limb defects) syndrome, an X-linked dominant, male-lethal disease (Konig et al. 2000).