The top 10 pathways were the following: Agrin Interactions at Neuromuscular Junction, PTEN Signaling, p53 Signaling, Oncostatin M Signaling, Cell Cycle: G1/S Checkpoint Regulation, CDK5 Signaling, Polyamine Regulation in Colon Cancer, Paxillin Signaling, Estrogen-Mediated S-phase Entry, and NF-κB Activation by Viruses. The gene discussed is PXN; the disease is colonic neoplasm.