The tumor in this case was an infiltrating solid, trabecular, and microglandular pattern and, in most ACC, the tumor cells were immunohistochemically positive for amylase, lysozyme, α1ACT, S-100 protein, and EMA but were negative for estrogen receptor, progesterone receptor, and HER2 protein (Table 2). This evidence concerns the gene ERBB2 and adrenal cortex carcinoma.