Three highly correlated SNPs (r2 > 0.9) in the PLA2G6 locus on chromosome 22q13.1 were significantly associated with primary tumor ulceration status, rs1028889 on chromosome 1p21.3 showed the strongest association with anatomic site, and rs966321 on chromosome 1p36.32 showed the strongest association with tumor thickness. Here, PLA2G6 is linked to neoplasm.