EN-RAGE was elevated in AKI (480 ± 450 ng/mL) in comparison with controls (60 ± 62 ng/mL), CKD 5 (190 ± 120 ng/mL), and HD (120 ± 100 ng/mL), all p < 0.001 (Figure 4). Here, AGER is linked to acute kidney injury.