With respect to indices of mineral and bone metabolism, we found that vitamin D insufficiency and excessive bone resorption were highly prevalent in both groups, but the poststroke group showed significantly higher mean levels of serum PTH and urinary bone resorption markers, lower values for osteocalcin, osteocalcin/BAP ratio, and a more pronounced imbalance between bone resorption and formation with resorption significantly exceeding formation. The gene discussed is BGLAP; the disease is vitamin D deficiency.