Regarding bone turnover status, compared to the rest of the cohort, patients with poststroke HF demonstrated a lower mean serum level of osteocalcin and higher mean levels of urinary bone resorption markers DPD/Cr (P = 0.004) and NTx/Cr (P = 0.056) resulting in a significantly higher negative BSI (resorption exceeds formation). The gene discussed is BGLAP; the disease is hydrops fetalis.