In multiple regression analyses adjusted for age, sex, HF type, 25(OH)D, PTH, eGFR, calcium, phosphate, and magnesium, history of stroke was an independent determinant of both higher DPD/Cr levels (β = 3.87, 95%CI 1.11–6.64, P = 0.006) and lower BSI (β = −4.17, 95%CI −7.29–1.06, P = 0.027). The gene discussed is PTH; the disease is Stroke.