IGHG3 and malaria: Assessing the acquired immune response against N-terminus PvMSP1, levels of IgG3 anti-ICB2-5 were higher in symptomless in Plasmodium vivax infected individuals than those of subjects who had acute malaria or those uninfected ones, raising importance of the N-terminus PvMSP1 to the rationale of malaria vaccine designs [42].