In line with the comparable effects on tumor growth and final tumor weights, 17-AAG treatment caused very similar decreases in the Ki67 staining for both HCT116 BAX+/− and HCT116 BAX−/− xenografts as determined on day five following daily i.p doses of 80mg/kg of the HSP90 inhibitor (Figure 6A and 6B). This evidence concerns the gene MKI67 and neoplasm.