BAX and cancer: As seen with sulindac sulfide, 96 hour SRB cell proliferation assays with 17-AAG gave significantly similar GI50 values for both members of the HCT116 isogenic cancer cell line pair (Figure 2A and Table 1; HCT116 BAX+/− 41.3nM ± 2.3 SEM, HCT116 BAX−/− 32.3nM ±1.3 SEM, P > 0.05).