EZR and cervical carcinoma: In particular, ezrin perinuclear localization showed a positive association with higher differentiation (75.3% in well differentiated, 44.2% in moderately differentiated, and 21.2% in poorly differentiated cervical cancers) and early stage cervical cancers (79.3% in early stage and 31.7% in advanced stage of cervical cancers) (Additional file 2: Table S2); however, apical membranous distribution of ezrin protein was only observed in normal cervical glands, but not in cervical cancer and its precancerous disease.