Age, gender, histology, degree of differentiation, TNM stage, lymph node metastasis, abnormal UNC5H4 expression and p53 mt-positive expression were analyzed in 70 patients, revealing p53 mt expression (P=0.006), lymph node metastasis (P=0.001), tumor stage (P=0.002) and degree of differentiation (P=0.044) as independent prognostic factors. The gene discussed is UNC5D; the disease is neoplasm.