PMP22 and neuropathy: Macroautophagy (hereafter referred to as autophagy) is also critical in PMP22-linked neuropathies as autophagosomes accumulate near protein aggregates within neuropathic Schwann cells and under permissive conditions, activating autophagy clears the misfolded PMP22 (Fortun et al., 2003, 2006, 2007).