CD8A and myeloid sarcoma: There is an association between HLA-A0301 of the MHC-I allele and susceptibility to MS, and it has been suggested that MHC-I is restricted to the CD8 T cells in the pathogenesis of MS, but otherwise, the allele HLA-A0201 of the MHC-I confers significant protection against disease [28, 49–51].