We evaluated liver and renal function tests, fasting blood glucose, calcium, phosphorus, prothrombin and partial thromboplastin times, thyroid function, tuberculin skin test, serology for brucella infection, hepatitis B and C, anti-cytomegalovirus IgM and IgG, human immunodeficiency virus, serology for toxoplasma infection, and workup for hydatid cyst and amebic and fungal infections to rule out renal failure. The gene discussed is F2; the disease is Renal insufficiency.