CRP and atherosclerosis: At present, we do not have any accurate biomarkers for the instability index.57 Nonetheless, several biomarkers have previously proved relatively efficient in the prediction of plaque instability (e.g., CRP, MMPs, and heat shock proteins).58-60 Recently, molecular imaging of atherosclerosis has demonstrated acceptable efficacy in animal studies, but such methods have yet to be fully explored in human studies.10