ESR1 and glioblastoma: Interestingly, for all apart from Th1 CD4+ cells (r2 = 0.05, p = 0.41), HUVEC (r2 = 0.002, p = 0.86) and glioblastoma (r2 = 0.05, p = 0.41), there was a significant correlation between the number of shared datasets at each ESR1 binding site and the enrichment for DNase I hypersensitivity peaks (Ecc-1 r2 = 0.75, p < 0.0001; Ishikawa r2 = 0.70, p < 0.0001; MCF7 r2 = 0.67, p = 0.0002; T47D plus estradiol r2 = 0.97, p < 0.0001; T47D r2 = 0.82, p < 0.0001; and LNCaP r2 = 0.61, p = 0.0006; Figure 3).