Correlation analyses between either total COX-2 (~66 + 74 kDa) or the 74 kDa protein alone versus the intracellular and extracellular protein parts of EGFR in tumor and mucosa tissue displayed positive relationships between COX-1, total COX-2 and the extracellular or intracellular parts of EGFR in mucosa tissue (p < 0.06-0.0007). This evidence concerns the gene PTGS1 and neoplasm.