Comparison of mean of MVD in the preinvasive and invasive carcinoma by CD31 showed that in preinvasive group mean MVD was 5.44 ± 2.21, and in the invasive group it was 12.82 ± 4.07 showing that MVD was higher in the invasive group, and it was also statistically significant P < 0.0001. Here, PECAM1 is linked to invasive carcinoma.