Furthermore, recent studies reported that the epithelial-mesenchymal transition (EMT), a process in which cells lose their epithelial features and acquire a mesenchymal fibroblastoid phenotype enhancing their motility and invasion capability, might also play a role in the development of resistance to EGFR-TKIs in NSCLC [17,18]. Here, EGFR is linked to non-small cell lung carcinoma.