TNFRSF12A and lupus nephritis: Other genes of interest include the TWEAK receptor FN14, whose expression on intrinsic renal cells promotes glomerulonephritis [17], ANKRD1, which is associated with proteinuria in SLE nephritis [18], TLRs 2 and 13, and several proteinase inhibitors of the Serpin family involved in the coagulation pathway.