CCR5 and AIDS: The possible efficacy of CCR5-targeting GT to cure AIDS has been strongly supported by the results of the “Berlin patient” who still has no detectable HIV-1 after receiving a hematopoietic stem/progenitor cell (HSC) transplantation from a CCR5Δ32 HLA-matched donor 6 years ago despite discontinuing antiviral therapy (118, 119).