In fact, The A(TA)nTAA element is the binding site for transcription factor IID, which is one of the factors responsible for the initiation of transcription and the presence of this longer A(TA)nTAA element in the promoter region of the gene for bilirubin UDP-glucuronosyltransferase 1 resulting in reduced expression of bilirubin-UGT1 (30% of normal) and hence causing unconjugated hyperbilirubinemia [3]. The gene discussed is UGT1A1; the disease is Hyperbilirubinemia.