While the lymphocyte-specific γ-interferon is not induced in NSCLC lines with AZA treatment, there is up-regulation of the interferon-γ receptor (IFNGR1) as well as of multiple STAT genes, including STAT1, the major IFNGR1 signal transducer (Fig. 1E). The gene discussed is IFNGR1; the disease is non-small cell lung carcinoma.