With respect to sensitization potential of this drug for immune responses, such targeting of DNMT's is known to induce increased expression of promoter DNA hypermethylated cancer testes antigens and also is reported to up-regulate other individual facets of the tumor immune stimulating profile, including major histocompatibility antigens, and transcription factors IRF7 and IRF5 [11-16]. The gene discussed is IRF7; the disease is cancer.