FARS2 and Cerebral atrophy: Interestingly, a recent report describes novel FARS2 mutations in two families with fatal intractable myoclonic epilepsy [20]; whilst the initial presenting symptom clearly correlates with our index case, there was no evidence of marked cerebral atrophy in our patient's brain MRI, which was a striking feature in the cases presented by these authors, although our patient did have structural brain abnormalities involving the corpus callosum and white matter abnormalities.