As studies of different ethnic populations are needed to ascertain the association between genetic polymorphisms of PAX9 and sporadic tooth agenesis [23], the purpose of this study was to investigate the relationship between two different single nucleotide polymorphisms (G-1031A and T-912C) (NCBI ref SNP ID: rs 2073247 and rs 2073244) of the PAX9 gene promoter region and hypodontia in a Turkish population which is a member of Caucasian racial family. Here, PAX9 is linked to Hypodontia.