Then we used different cutoff levels of AFP (400 ng/ml, 200 ng/ml and 100 ng/ml, respectively) to subgroup the 272 HCC patients and evaluated the prognostic significance of LARP1in the patient subgroups.Our data suggested that AFP cut-off values of 200 ng/ml or 100 ng/ml) were significantly predictive of patient survival, whereas AFP = 400 ng/ml was not a prognostic cut-off. Here, AFP is linked to hepatocellular carcinoma.