IL12A and kidney disorder: In the logistic regressions that included gender, age, RRT vintage, kidney diseases, liver enzymes, anti-HCV, and polymorphic variants of IL-12A, there was a positive association of anti-HBs development in response to hepatitis B vaccination with concurrently RRT vintage (OR 1.3, 95 % CI 1.2–1.5, P < 0.001), chronic glomerulonephritis (OR 2.6, 95 % CI 1.2–5.4, P = 0.012), and GA IL-12A (OR 1.6, 95 % CI 1.0–2.5, P = 0.035); a negative association was shown with age (OR 0.98, 95 % CI 0.97–1.0, P = 0.018) (P < 0.001 for the significance of this model).