NPPB and infarction: The primary purpose of the OAT Biomarker substudy was to evaluate the impact of mechanical revascularization on paired levels of N-terminal prohormone of brain natriuretic peptide (NT-proBNP) obtained at baseline and at 1 year of follow up; and secondly to assess the impact of the randomized treatment on dynamics of biomarkers related to post-infarction left ventricular remodeling, fibrosis and angiogenesis, including matrix metalloproteinases (MMP) 2 and 9 and tissue inhibitor of matrix metalloproteinase 2 (TIMP-2), Vascular Endothelial Growth Factor (VEGF), and galectin-3.