ANGPT1 and polycystic ovary syndrome: In addition, the Ang-1/Ang-2 ratio was significantly decreased in follicular fluid of PCOS compared with non-PCOS women (0.02 ± 0.004 vs. 0.04 ± 0.006, p = 0.002), consistent with increased follicular fluid Ang-2 levels in the PCOS group (Table 2).