The Ang-1/Ang-2 ratio in serum of PCOS women was significantly increased compared with non-PCOS women at all three measured time points, on day 3 (39.7 ± 2.3 vs. 24.9 ± 2.6, p = 0.02), day of hCG administration (39.2 ± 2.9 vs. 28.5 ± 1.7, p = 0.04), and day of oocyte retrieval (38.2 ± 3.1 vs. 27.3 ± 1.9, p = 0.01) (Table 2). The gene discussed is ANGPT2; the disease is polycystic ovary syndrome.