According to a previous report, median TS and DPD protein levels in various cancers including head and neck, gastric, colorectal, breast, lung, and pancreatic cancers were 22.1 and 134.8 ng/mg, respectively, and the mean ± SD of TS and DPD protein levels were 39.9 ± 53.8 and 159.8 ± 116.3 ng/mg, respectively. Here, TYMS is linked to familial pancreatic carcinoma.